Symbioflor 1 N1 1 x 50 ml - Produktabbildung von vorne mit Flasche - PZN 00996086

For recurrent inflammation of the sinuses and bronchi

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Protection against recurrent respiratory diseases

Bronchitis and sinusitis are among the most common respiratory conditions. Infections generally resolve within a few days. If our immune system is too weak, infections can become chronic. Symbioflor® 1 modulates the immune system with the aid of living Enterococcus faecalis bacteria, thereby significantly reducing the incidence of new or recurrent infections in patients with recurrent diseases of the upper and lower respiratory tracts.


Contains living Enterococcus faecalis bacteria


Modulates the body’s immune system and greatly reduces the recurrence of sinusitis


Recurrent inflammation of the upper and lower respiratory tracts

Symbioflor® 1 is the only approved probiotic drug in the world with living Enterococcus faecalis bacteria.

How does Symbioflor® 1 work?

The probiotic drug Symbioflor® 1 contains immunomodulatory bacteria. When Symbioflor® 1 is ingested, these bacteria find their way into the gut. The intestinal mucosa is the largest mucous membrane in our body. Around 80% of immune cells are located here. We are the only pharmaceutical manufacturer in the world to make use of living Enterococcus faecalis bacteria. 
In patients with recurrent bronchitis, treatment with Symbioflor® 1 results in far fewer recurrent respiratory tract infections – the relapse rate is significantly reduced. Studies were also able to demonstrate that infections occurring during treatment were less severe.

The advantages of Symbioflor® 1:

  • Proven efficacy in clinical studies

  • Only probiotic drug in the world with living Enterococcus faecalis bacteria

  • Very gentle treatment with minimal side effects

  • No preservatives

  • No alcohol

Symbioflor® 1 is available in any pharmacy!

Symbioflor® 1

What causes recurrent sinusitis?

Sinusitis is inflammation of the mucous membranes lining the sinuses. In the course of a cold, if there is insufficient air flow through the nose the secretions cannot drain completely. As a consequence, the mucosa of the nose and sinuses can become inflamed. The mucosa swells, potentially constricting the nasal passage even further and causing the secretions to back up into the sinuses. In medical terms this is known as acute sinusitis. In this acute phase, antibiotics are frequently prescribed, in order to rapidly eliminate the pathogens responsible for the infection.

If acute sinusitis does not heal completely or the inflammatory mechanism in the nasal mucosa is disrupted, new tissue may form in the inflamed area. If this results in a bulge in the nasal mucosa, doctors call this a polyp. The newly formed tissue can permanently impair ventilation of the nose, thereby resulting in recurrent sinusitis. In recurrent sinusitis, the symptoms are less severe than with an acute infection. However, recurrent sinusitis sufferers are less resilient, suffer from general exhaustion and are more susceptible to all types of infection. Recurrent sinusitis can significantly reduce quality of life.

Eine Frau liegt krank im Bett und hustet.

What causes recurrent bronchitis?

Bronchitis is an inflammation of the lower respiratory tract. It most commonly arises when pathogens, such as bacteria or viruses, find their way into the lung tissue. This usually occurs via the breath, but they can also be carried in the bloodstream. The pathogens are identified by the immune system and trigger a defensive inflammatory response. A well-protected mucosa and an adequate defence system can effectively protect the respiratory tract against such infections. 

However, if there is permanent irritation of the bronchial mucosa or the immune system is weakened, this may lead to the bronchitis becoming entrenched and chronic. This is known as recurrent bronchitis. Recurrent bronchitis places a permanent strain on the individual, which can affect other areas of the body. Recurrent bronchitis sufferers frequently experience relapses, i.e. recurrent respiratory tract infections.

Unless otherwise prescribed, the following dose guidelines apply:

Adults take 30 drops 3x daily (in the morning on getting up, at midday before eating and in the evening before going to bed). Keep the drops in your mouth for a while and gargle before swallowing.

Shake well before use. This produces a slight cloudiness.

Symbioflor® 1 is suitable for reducing the recurrence rate of recurrent upper and lower respiratory tract infections and can therefore be taken preventively.

The active substance is: Bacterial culture (1.0 ml) with Enterococcus faecalis bacteria (DSM 16440, cells and autolysate) corresponding to 1.5 – 4.5 x 107 live cells.

1 ml = 12 drops

The other ingredients are: Lactose monohydrate, cystine, sodium carbonate decahydrate, sodium chloride, magnesium sulphate heptahydrate, potassium chloride, calcium chloride dihydrate, magnesium chloride hexahydrate, purified water, standard I nutrient broth (peptone [from casein], dry yeast extract, sodium chloride, glucose monohydrate, purified water).

Do not store Symbioflor® 1 above 30 °C before opening. Do not freeze. Close the bottle tightly immediately after use and store in a refrigerator (2 °C - 8 °C). After the bottle is first opened, the contents can be stored for 4 weeks.

You can download the package leaflet for Symbioflor® 1 in pdf format here. Version: December 2020


Symbioflor® 1 drops for oral use, suspension

Active ingredient: Enterococcus faecalis bacteria 

Therapeutic indications: To reduce the recurrence rate of recurrent upper and lower respiratory tract infections, particularly sinusitis and bronchitis. 

Warning: Contains lactose and glucose 

For risks and side effects, read the package leaflet and ask your doctor or pharmacist. 

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