Symbioflor® 2 - for irritable bowel syndrome
The medicine Symbioflor® 2
- contains the natural intestinal bacterium E. coli
- regulates the activity of the intestine
- helps with irritable bowel syndrome
- is suitable for children
The bacteria-containing medicine Symbioflor® 2
Symbioflor® 2 is suitable for the treatment of stomach- intestinal complaints, especially irritable bowel syndrome. The affected suffer from abdominal pain, constipation or diarrhoea, without recognisable causes.
The intestinal microflora of a patient suffering from irritable bowel syndrome is different from that of a healthy person. The composition of the microflora also appears to be less stable.
Symbioflor® 2 contains a high concentration of the natural intestinal bacterium E. coli. The preparation can regulate the activity of the intestine and combat the discomforts of irritable bowel syndrome causatively.
Symbioflor® 2 is available in any German pharmacy.
1 ml (14 drops) of Symbioflor® 2 contain: bacteria culture (1,0 ml) containing Escherichia coli bacteria (DSM 17252, cells and autolysate) equivalent to 1,5 to 4,5 x 107 living cells.
Further ingredients: sodium chloride, magnesium sulfate 7 H2O, potassium chloride, calcium chloride 2 H2O, magnesium chloride 6 H2O und purified water.
Indications: Immunomodulation and disorders of the gastrointestinal function, especially irritable bowel syndrome (Colon irritabile).
Contraindications: Not to be taken if you are hypersensitive (allergic) to the active agent or any of the other ingredients. Symbioflor® 2 must not be taken during acute cholecystitis, acute pancreatitis or in the case of obstruction of the bowels. Discontinue during acute feverish illnesses.
Side effects: Symbioflor® 2 is generally well tolerated. On commencement of treatment, distension of the abdomen, release of wind or upper abdominal pain may occur occasionally.
Should any signs of the above side effects occur on commencement of treatment, the dosage should be changed. Either take Symbioflor® 2 in more diluted form or in smaller quantities or alternatively increase the number of drops more slowly.
Interactions with other drugs: No interactions are known.
Ask your doctor or pharmacist about any health risks and possible side effects.
Unless otherwise prescribed by your doctor, the following dosage regulations apply:
Adults: On commencement of treatment 10 drops, 3x daily, at meal times. After one week the dosage should be increased to 20 drops 3x daily
Paediatric population:The drug is not approved for children, therefore no dosage recommendation can be given for children. However, there is an observational study in children, which is assessed by the European Medicines Agency (EMA) as follows:
“In a non-interventional study with 203 children aged 4 – 18 years, that were diagnosed for having irritable bowel syndrome (IBS) based on the ROM III criteria for children, the overall assessment of efficacy for all 4 IBS subtypes was very good to good in more than 80 % of the children.'"*
“The overall assessment of tolerability was good to very good in more than 98 % of the children.“*
* Summary of product characteristics for Symbioflor 2, effective date 05/2018
Shake well before use. This makes the liquid slightly cloudy.
Storage life: 2 years. After the bottle is open for the first time, the content is at least 3 weeks stable.
How to store: Store Symbioflor® 2 below 30ºC before opening. Do not freeze.
Close the bottle properly immediately after use and keep in the refrigerator (2ºC - 8ºC).
Symbioflor® 2 does not contain any stabilisers and is therefore easily contaminated if not handled correctly. Such contamination is avoided by only opening the bottle briefly when using the product and by allowing the contents to flow carefully drop by drop from the dropper. Do not touch the dropper! Due to the high surface tension of Symbioflor® 2, problems cannot be entirely avoided when starting and stopping release of the drops. Lightly tapping the base of the bottle while holding it at an angle will cause the drops to flow more easily. The rate of flow can be influenced by varying the angle at which the bottle is held.